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Human colon stem cells are the predominant epithelial responders to bacterial antigens

Intestinal epithelial cells (IECs) are capable of mounting an adequate antimicrobial inflammatory response to pathogens while tolerating commensals. The underlying regulatory mechanisms of immune sensitivity remain incompletely understood, particularly in the context of human IECs. To enhance our un...

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Главные авторы: Maaike H. De Vries, Claartje A. Meddens, Hemme J. Hijma, Anne-Claire Berrens, Suze A. Jansen, Berend A. P. Kooiman, Scott Snapper, Hans Clevers, Michal Mokry, Ewart W. Kuijk, Edward E. S. Nieuwenhuis
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2025-10-01
Серии:Frontiers in Immunology
Предметы:
intestinal stem cells
intestinal epithelium
innate immunity
immune regulation
WNT pathway
inflammatory bowel disease
Online-ссылка:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1677943/full
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