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Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma.

Neoadjuvant chemoradiation therapy (CRT) is increasingly the standard of care for locally advanced oesophageal cancer. A complete pathological response to CRT is associated with a favourable outcome. Radiation therapy is important for local tumour control, however, radioresistance remains a substant...

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Huvudupphov: Niamh Lynam-Lennon, Stephen G Maher, Aoife Maguire, James Phelan, Cian Muldoon, John V Reynolds, Jacintha O'Sullivan
Materialtyp: Artigo
Språk:Inglês
Utgiven: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC4072695?pdf=render
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