Reconsidering Digoxin in Atrial Fibrillation: From Historical Controversy to Physiologically Guided and Personalized Rate Control

<b>Background</b>: The role of digoxin in atrial fibrillation, particularly in patients with heart failure, has long been debated. Observational studies reporting higher mortality have fueled skepticism, yet growing evidence suggests that these findings largely reflect prescription bias, confounding...

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Autori principali:	Silvia Ana Luca, Adelina Andreea Faur-Grigori, Cristina Văcărescu, Dragos Cozma, Simina Crișan, Dan Gaiță, Mihai-Andrei Lazăr, Constantin-Tudor Luca
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-12-01
Serie:	Biomedicines
Soggetti:	atrial fibrillation digoxin heart failure rate control serum digoxin concentration confounding by indication
Accesso online:	https://www.mdpi.com/2227-9059/13/12/3098
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