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PEP-19 modulates calcium binding to calmodulin by electrostatic steering

The protein PEP-19 increases the rates of calcium binding to calmodulin. Here, the authors report the structure of PEP-19 bound to the C-terminal domain of calmodulin, and are able to propose a mechanism for the observed increased calcium association rate.

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Autors principals: Xu Wang, John A. Putkey
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2016-11-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/ncomms13583
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