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The FHA domain protein ArnA functions as a global DNA damage response repressor in the hyperthermophilic archaeon Saccharolobus islandicus

ABSTRACT Forkhead-associated (FHA) domain proteins specifically recognize phosphorylated threonine via the FHA domain and are involved in signal transduction in various processes especially DNA damage response (DDR) and cell cycle regulation in eukaryotes. Although FHA domain proteins are found in p...

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Main Authors: Zhichao Jiang, Zijia Lin, Qi Gan, Pengju Wu, Xuemei Zhang, Yuanxi Xiao, Qunxin She, Jinfeng Ni, Yulong Shen, Qihong Huang
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2023-08-01
Series:mBio
Subjects:
FHA domain
archaea
DNA damage response
protein phosphorylation
signal transduction
transcription regulation
Online Access:https://journals.asm.org/doi/10.1128/mbio.00942-23
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