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PLGA-Encapsulated Elvitegravir and Curcumin Modulates ART Penetration, Oxidative Stress, and Inflammation

<b>Background/Objectives:</b> HIV persists in central nervous system (CNS) reservoirs, where infected microglia and macrophages drive neuroinflammation, oxidative stress, and neuronal damage, contributing to HIV-associated neurocognitive disorder (HAND). Nanoparticle-based drug delivery systems, par...

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Principais autores: Sandip Godse, Lina Zhou, Namita Sinha, Golnoush Mirzahosseini, Santosh Kumar
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-03-01
Serier:Brain Sciences
Fag:
HIV
HAND
BBB
elvitegravir
curcumin
PLGA
Online adgang:https://www.mdpi.com/2076-3425/15/4/328
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