Development and characterization of a self-nano emulsifying drug delivery system (SNEDDS) for Ornidazole to improve solubility and oral bioavailability of BCS class II drugs

Abstract This study aimed to investigate the in vitro performance of self-nanoemulsifying drug delivery systems (SNEDDSs) of Ornidazole (ORD), a poorly water-soluble drug. Self-nanoemulsifying drug delivery systems of ORD were prepared using various oils, non-ionic surfactants, and/or water-soluble...

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Bibliografische Detailangaben

Hauptverfasser:	Popat Mohite, Shruti Sule, Anil Pawar, Hanan M. Alharbi, Swastika Maitra, Vetriselvan Subramaniyan, Vinoth Kumarasamy, Daniel Ejim Uti, Celestine O. Ogbu, Simon Inedu Oodo, Ajoy Kumer, Ayodeji Oluwafemi Idowu, Okechukwu N. N. Okoye
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2024-11-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Ornidazole self-nano emulsifying system Surfactant Cosurfactant, solubility
Online-Zugang:	https://doi.org/10.1038/s41598-024-73760-7
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