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Genomic conservation and CNS-associated intra-host variation of Nipah virus during the 1998-1999 Malaysian outbreak

Objectives: Nipah virus (NiV) is a highly pathogenic henipavirus responsible for recurrent outbreaks of severe encephalitis. This study aimed to address gaps in historical genomic data by characterizing NiV genomes recovered from archived central nervous system (CNS) tissues from the 1998 to 1999 Ma...

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Hlavní autoři: Heng Choon Cheong, Foo Hou Tan, Hui Ming Ong, Kum Thong Wong, Kien Chai Ong, Soon Hao Tan, Chong Tin Tan, Li Ping Wong, Jie Ping Schee, Rozainanee Mohd-Zain, Aziyah Mat Rahim, Nuryana Idris, Kok Keng Tee, Li-Yen Chang
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2026-09-01
Edice:International Journal of Infectious Diseases
Témata:
Central nervous system
Henipavirus
Phylogenetics
Quasispecies
Intra-host evolution
On-line přístup:http://www.sciencedirect.com/science/article/pii/S1201971226005291
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