Efficacy of photodynamic therapy using 5-aminolevulinic acid-induced photosensitization is enhanced in pancreatic cancer cells with acquired drug resistance

The use of 5-aminolevulinic acid (ALA) as a precursor for protoporphyrin IX (PpIX) is an established photosensitization strategy for photodynamic therapy (PDT) and fluorescence guided surgery. Ongoing studies are focused on identifying approaches to enhance PpIX accumulation as well as to identify t...

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Detalhes bibliográficos

Principais autores:	Yiran Liu, Sally Kyei Mensah, Sergio Farias, Shakir Khan, Tayyaba Hasan, Jonathan P. Celli
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-12-01
Colecção:	Photodiagnosis and Photodynamic Therapy
Assuntos:	Photodynamic therapy (PDT) Drug resistance Protoporphyrin IX (PpIX) 5-aminolevulinic acid (ALA) 3D cell culture Pancreatic cancer
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1572100024003995
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