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Molecular evolution of the transmembrane domains of G protein-coupled receptors.

G protein-coupled receptors (GPCRs) are a superfamily of integral membrane proteins vital for signaling and are important targets for pharmaceutical intervention in humans. Previously, we identified a group of ten amino acid positions (called key positions), within the seven transmembrane domain (7T...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Sarosh N Fatakia, Stefano Costanzi, Carson C Chow
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2011-01-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC3221663?pdf=render
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