Downregulated DUXAP8 lncRNA impedes trophoblast cell proliferation and migration by epigenetically upregulating TFPI2 expression

Abstract Background Preeclampsia (PE), a pregnancy complication characterized by new-onset hypertension and proteinuria during the second trimester, is the leading cause of neonatal and maternal morbidity and mortality. In the etiology of PE, failure of uterine spiral artery remodeling may be relate...

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Bibliografische gegevens

Hoofdauteurs:	Xiaotong Tang, Yueying Cao, Dan Wu, Lizhou Sun, Yetao Xu
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2023-06-01
Reeks:	Reproductive Biology and Endocrinology
Onderwerpen:	Preeclampsia lncRNA DUXAP8 EZH2 TFPI2
Online toegang:	https://doi.org/10.1186/s12958-023-01108-3
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