Potential diagnostic value of CSF metabolism-related proteins across the Alzheimer’s disease continuum

Abstract Background Alzheimer’s disease (AD) cerebrospinal fluid (CSF) core biomarkers (Aβ42/40 ratio, p-tau, and t-tau) provide high diagnostic accuracy, even at the earliest stage of disease. However, these markers do not fully reflect the complex AD pathophysiology. Recent large scale CSF proteom...

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Autores principales:	Silvia Paciotti, Anna Lidia Wojdała, Giovanni Bellomo, Andrea Toja, Elena Chipi, Sander R. Piersma, Thang V. Pham, Lorenzo Gaetani, Connie R. Jimenez, Lucilla Parnetti, Davide Chiasserini
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2023-07-01
Colección:	Alzheimer’s Research & Therapy
Materias:	Alzheimer’s disease Cerebrospinal fluid Biomarkers Preclinical AD Pyruvate kinase Aldolase
Acceso en línea:	https://doi.org/10.1186/s13195-023-01269-8
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