The preclinical study of biocompatibility of tyrosine polycarbonate bioresorbable scaffold in small caliber porcine peripheral arteries

Abstract Drug-eluting resorbable scaffolds (DRS) are conceptually attractive for treatment of peripheral arterial disease, particularly below-the-knee. MOTIV is a peripheral variant of REVA Medical’s well-established, radiopaque tyrosine-polycarbonate (Tyrocore) sirolimus-eluting DRS. The purpose of...

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Autors principals:	Mateusz Kachel, Pedro H. C. Melo, Yanping Cheng, Gerard B. Conditt, Danielle Gram, Jeffrey Anderson, Serge D. Rousselle, Sahil A. Parikh, Juan F. Granada, Grzegorz L. Kaluza
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-03-01
Col·lecció:	Scientific Reports
Matèries:	Below-the-knee Bioresorbable scaffolds Animal model Peripheral arterial disease Chronic limb threatening ischemia Tyrocore
Accés en línia:	https://doi.org/10.1038/s41598-025-91759-6
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