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Role of β and α1-adrenoceptors in pancreatic regulation of glucose homeostasis, apoptosis, and fibrosis in dexamethasone-treated rats: A new insight into β-arrestin2 crosstalk with cAMP, PKA-ERK1/2-CREB, and PKB-FOXO1 signaling pathways

Objective: The current study aimed to investigate the role of β and α1-adrenoceptors in pancreatic regulation of glucose homeostasis, apoptosis, and fibrosis in a rat model of dexamethasone-induced insulin resistance. Introduction: Insulin resistance is a hallmark of metabolic syndrome and is often...

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Principais autores: Nehal S. Wahba, Ahmed Abdelfattah-Hassan, Dalia A. Hemead, Alaa S. Wahba, Islam A.A.E.-H. Ibrahim, Mona F. Mahmoud, Maryam A. AL-Ghamdi, Etimad Huwait, Mostafa E. El-Naggar
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2025-09-01
coleção:International Journal of Immunopathology and Pharmacology
Acesso em linha:https://doi.org/10.1177/03946320251365089
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