1,25-dihydroxyvitamin-D3 distinctly impacts the paracrine and cell-to-cell contact interactions between hPDL-MSCs and CD4+ T lymphocytes

IntroductionHuman periodontal ligament-derived mesenchymal stromal cells (hPDL-MSCs) possess a strong ability to modulate the immune response, executed via cytokine-boosted paracrine and direct cell-to-cell contact mechanisms. This reciprocal interaction between immune cells and hPDL-MSCs is influen...

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Auteurs principaux:	Christian Behm, Oliwia Miłek, Katharina Schwarz, Xiaohui Rausch-Fan, Andreas Moritz, Oleh Andrukhov
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2024-09-01
Collection:	Frontiers in Immunology
Sujets:	mesenchymal stromal cells periodontal ligament immunomodulation 1,25-dihydroxyvitamin-D3 paracrine mechanisms direct cell-to-cell contact
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1448597/full
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