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Hfq Globally Binds and Destabilizes sRNAs and mRNAs in <named-content content-type="genus-species">Yersinia pestis</named-content>

ABSTRACT Hfq is a ubiquitous Sm-like RNA-binding protein in bacteria involved in physiological fitness and pathogenesis, while its in vivo binding nature remains elusive. Here we reported genome-wide Hfq-bound RNAs in Yersinia pestis, a causative agent of plague, by using cross-linking immunoprecipi...

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Principais autores: Yanping Han, Dong Chen, Yanfeng Yan, Xiaofang Gao, Zizhong Liu, Yaqiang Xue, Yi Zhang, Ruifu Yang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019-08-01
coleção:mSystems
Assuntos:
CLIP-seq
Hfq
RNA degradation
Y. pestis
sRNA
Acesso em linha:https://journals.asm.org/doi/10.1128/mSystems.00245-19
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