Novel NAC-loaded poly(lactide-co-glycolide acid) nanoparticles for cataract treatment: preparation, characterization, evaluation of structure, cytotoxicity, and molecular docking studies

Background N-acetylcarnosine (NAC), a dipeptide with powerful antioxidant properties that is extensively used as a pharmaceutical prodrug for the treatment of cataract and acute gastric disease, was investigated by molecular dynamics with the GROMACS program in order to understand the solvent effect...

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Detalhes bibliográficos

Principais autores:	Yasemin Budama-Kilinc, Rabia Cakir-Koc, Serda Kecel-Gunduz, Yagmur Kokcu, Bilge Bicak, Hande Mutlu, Aysen E. Ozel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	PeerJ Inc. 2018-01-01
coleção:	PeerJ
Assuntos:	NAC Molecular dynamic Zeta-sizer GROMACS TEM FTIR
Acesso em linha:	https://peerj.com/articles/4270.pdf
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