Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the Specificity of DNA Recognition by the POU-Domain Factors OCT1 and OCT2 in a Monomeric Configuration

BOB1, a mammalian lymphocyte-specific transcriptional coactivator of the transcription factors OCT1 and OCT2 (OCT1/2), plays important roles in normal immune responses, autoimmunity, and hematologic malignancies. The issue of a DNA sequence preference change imposed by BOB1 was raised more than two...

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Detalhes bibliográficos

Principais autores:	Igor B. Nazarov, Danil S. Zilov, Mikhail N. Gordeev, Evgenii V. Potapenko, Nataliya Yeremenko, Alexey N. Tomilin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-01-01
coleção:	Biomolecules
Assuntos:	BOB1 OCA-B OBF1 OCT1 OCT2 transcription factor specificity
Acesso em linha:	https://www.mdpi.com/2218-273X/14/1/123
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