OTUD3 suppresses the mTORC1 signaling by deubiquitinating KPTN

Background: Ubiquitination and deubiquitination modifications play pivotal roles in eukaryotic life processes, regulating protein dynamics via the ubiquitin-proteasome pathway. Dysregulation can impact disease development, including cancer and neurodegenerative disorders. Increasing evidence highlig...

詳細記述

書誌詳細

主要な著者:	Jiatao Li, Dan Yang, Yan Lin, Wei Xu, Shi-min Zhao, Chenji Wang
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2024-01-01
シリーズ:	Frontiers in Pharmacology
主題:	OTU domain-containing protein 3 KPTN deubiquitination mTORC1 KICSTOR
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1337732/full
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