Copper overload impairs hematopoietic stem and progenitor cell proliferation via prompting HSF1/SP1 aggregation and the subsequently downregulating FOXM1-Cytoskeleton axis

Summary: Unbalanced Cu homeostasis has been suggested to be associated with hematopoietic disease, but the roles of Cu overload in the hematopoietic system and the potential mechanisms are obscure. Here, we report a novel association and the novel potential pathways for Cu overload to induce prolife...

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主要な著者:	LingYa Li, ZhiPeng Tai, WenYe Liu, Yi Luo, You Wu, ShuHui Lin, Mugen Liu, BaoXiang Gao, Jing-Xia Liu
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2023-04-01
シリーズ:	iScience
主題:	Molecular biology Cell biology Stem cells research
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2589004223004832
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