Passive Transfer of Animal-Derived Polyclonal Hyperimmune Antibodies Provides Protection of Mice from Lethal Lassa Virus Infection

Background: Lassa virus (LASV) can cause severe acute systemic infection in humans. No approved antiviral drugs or vaccines are currently available. Antibody-based therapeutics are considered a promising treatment strategy in the management of LASV disease. Methods: We used chimeric Ifnar<sup>−/−</s...

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Principais autores:	Lisa Oestereich, Helena Müller-Kräuter, Elisa Pallasch, Thomas Strecker
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-06-01
Colecção:	Viruses
Assuntos:	Lassa mammarenavirus Lassa fever arenavirus virus-like particle neutralizing antibodies in vivo protection
Acesso em linha:	https://www.mdpi.com/1999-4915/15/7/1436
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