Extracellular Redox Regulation of α7β Integrin-Mediated Cell Migration Is Signaled via a Dominant Thiol-Switch

While adhering to extracellular matrix (ECM) proteins, such as laminin-111, cells temporarily produce hydrogen peroxide at adhesion sites. To study the redox regulation of α7β1 integrin-mediated cell adhesion to laminin-111, a conserved cysteine pair within the α-subunit hinge region...

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Autori principali:	Lukas Bergerhausen, Julius Grosche, Juliane Meißner, Christina Hecker, Michele F. Caliandro, Christoph Westerhausen, Andrej Kamenac, Maryam Rezaei, Matthias Mörgelin, Gereon Poschmann, Dietmar Vestweber, Eva-Maria Hanschmann, Johannes A. Eble
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2020-03-01
Serie:	Antioxidants
Soggetti:	redox regulation redox signaling integrin α7β1 thiol-switch extracellular thioredoxin-1 laminin binding cell migration
Accesso online:	https://www.mdpi.com/2076-3921/9/3/227
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