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Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation

Summary: In vitro models of neuronal aging and gene manipulation in human neurons (hNeurons) are valuable tools for investigating human brain aging and diseases. Here, we present a protocol for applying human embryonic stem cell (hESC)-derived neurons to model aging and the further application of sm...

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Principais autores: Hui Zhang, Shuhui Sun, Juan Carlos Izpisua Belmonte, Guang-Hui Liu, Si Wang, Weiqi Zhang, Jing Qu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-03-01
Serier:STAR Protocols
Fag:
Cell Biology
Developmental biology
Molecular Biology
Neuroscience
Stem Cells
Cell Differentiation
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666166725000395
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