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The genomic stability regulator PTIP is required for proper chromosome segregation in mitosis

Abstract Background The Pax transcription activation domain-interacting protein (PTIP) is a nuclear protein that is an essential component of H3K4 methylation for gene activation in vascular, kidney, B cell, and adipocyte development. Furthermore, it plays a key role in genomic stability in higher e...

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Tallennettuna:
Päätekijät: Fengxia Zhang, Mingxuan Wei, Haoran Chen, Liting Ji, Yan Nie, Jungseog Kang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2022-09-01
Sarja:Cell Division
Aiheet:
Chromosome segregation
Mitosis
Genetic instability
Centrosome
DNA damage
PTIP
Linkit:https://doi.org/10.1186/s13008-022-00081-4
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