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The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA.

<h4>Background</h4>IL-24 (melanoma differentiation-associated gene-7 (mda-7)), a member of the IL-10 cytokine family, possesses the properties of a classical cytokine as well as tumor suppressor effects. The exact role of IL-24 in the immune system has not been defined but studies have indicated a r...

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Autori principali: Kristian Otkjaer, Helmut Holtmann, Tue Wenzel Kragstrup, Søren Riis Paludan, Claus Johansen, Matthias Gaestel, Knud Kragballe, Lars Iversen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2010-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0008671&type=printable
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