Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation

Abstract Background Testosterone contributes to male organism development, such as bone density, muscle development, and fat repartition. Estrogen (derived from testosterone) also contributes to female reproductive system development. Here, we investigated the effect of testosterone on glioma cells...

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Detalhes bibliográficos

Principais autores:	Kouminin Kanwore, Konimpo Kanwore, Xiaoxiao Guo, Ying Xia, Han Zhou, Lin Zhang, Gabriel Komla Adzika, Adu-Amankwaah Joseph, Ayanlaja Abdulrahman Abiola, Peipei Mu, Piniel Alphayo Kambey, Marie Louis N’dzie Noah, DianShuai Gao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-10-01
coleção:	Inflammation and Regeneration
Assuntos:	Glioma Testosterone GDNF Cyclophilin A Neuroprotection Neuroinflammation
Acesso em linha:	https://doi.org/10.1186/s41232-023-00300-7
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