CFTR modulators partially restore the epithelial interferome in Aspergillus infection to improve clinical outcomeResearch in context

Summary: Background: The impact of CFTR modulator therapy on host immunity and outcomes in people with Cystic Fibrosis (CF)-related Aspergillus lung disease is poorly defined. We aimed to characterise fungal-relevant clinical outcomes post-CFTR modulators and assess effects on the Aspergillus-depen...

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Главные авторы:	Sarah L. Laverty, Imogen Felton, Michelle Casey, Benjamin Hopwood, Nicholas Simmonds, Darius Armstrong-James, Anand Shah, Peter Kelleher
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2026-02-01
Серии:	EBioMedicine
Предметы:	Cystic fibrosis Aspergillus Interferon Immunity Neutrophil
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2352396426000125
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