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Keap1/Nrf2 Signaling: A New Player in Thyroid Pathophysiology and Thyroid Cancer

The Keap1/Nrf2 pathway is a key mediator of general redox and tissue-specific homeostasis. It also exerts a dual role in cancer, by preventing cell transformation of normal cells but promoting aggressiveness, and drug resistance of malignant ones. Although Nrf2 is well-studied in other tissues, its...

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Bibliografiset tiedot
Päätekijät: Cedric O. Renaud, Panos G. Ziros, Dionysios V. Chartoumpekis, Massimo Bongiovanni, Gerasimos P. Sykiotis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019-08-01
Sarja:Frontiers in Endocrinology
Aiheet:
Linkit:https://www.frontiersin.org/article/10.3389/fendo.2019.00510/full
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