A Novel ELISA Assay for the Detection of Anti-Prothrombin Antibodies in Antiphospholipid Syndrome Patients at High Risk of Thrombosis

Autoantibodies targeting prothrombin (aPT) can be found in antiphospholipid syndrome (APS) patients. However, their detection has proven difficult to standardize. Here, we developed a new ELISA assay to improve the identification of aPT and compared its performance with currently available anti-phos...

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Autors principals:	Mathivanan Chinnaraj, Vittorio Pengo, Nicola Pozzi
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-09-01
Col·lecció:	Frontiers in Immunology
Matèries:	antiphospholipid antibody syndrome autoimmunity acquired coagulation disorders lipid-protein interaction single-molecule biophysics COVID-19
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.741589/full
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