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Inhibition of β-catenin signaling attenuates arteriovenous fistula thickening in mice by suppressing myofibroblasts

Abstract Background Arteriovenous fistula (AVF) is the most important vascular access for hemodialysis; however, preventive treatment to maintain the patency of AVFs has not been developed. In endothelium, β-catenin functions in both the intercellular adherens complex and signaling pathways that ind...

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Principais autores: Chung-Te Liu, Shih-Chang Hsu, Hui-Ling Hsieh, Cheng-Hsien Chen, Chun-You Chen, Yuh-Mou Sue, Tso-Hsiao Chen, Yung-Ho Hsu, Feng-Yen Lin, Chun-Ming Shih, Yan-Ting Shiu, Po-Hsun Huang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-01-01
Serier:Molecular Medicine
Fag:
Arteriovenous fistula (AVF)
β-catenin
Hemodialysis
Myofibroblast
Online adgang:https://doi.org/10.1186/s10020-022-00436-1
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