In-silico study of E169G and F242K double mutations in leucine-rich repeats (LRR) polygalacturonase inhibiting protein (PGIP) of Gossypium barbadense and associated defense mechanism against plant pathogens

Abstract Background Polygalacturonase inhibiting proteins (PGIPs) play a pivotal role in plant defense against plant pathogens by inhibiting polygalacturonase (PG), an enzyme produced by pathogens to degrade plant cell wall pectin. PGIPs, also known as leucine-rich repeat pathogenesis-related (PR) p...

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Autori principali:	Sneha Murmu, Mayank Rashmi, Dipak T. Nagrale, Tejasman Kour, Mahender Kumar Singh, Anurag Chaurasia, Santosh Kumar Behera, Raja Shankar, Rajiv Ranjan, Girish Kumar Jha, Shailesh P. Gawande, Neelakanth S. Hiremani, Y. G. Prasad, Sunil Kumar
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-01-01
Serie:	Journal of Cotton Research
Soggetti:	Polygalacturonase inhibiting proteins Polygalacturonase Plant-pathogen interaction Protein-protein interaction Docking Molecular dynamics simulation
Accesso online:	https://doi.org/10.1186/s42397-024-00203-z
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