Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80

Acetylation of protein N-termini is one of the most common protein modifications in the eukaryotic cell and is catalyzed by the N-terminal acetyltransferase family of enzymes. The N-terminal acetyltransferase NAA80 is expressed in the animal kingdom and was recently found to specifically N-terminall...

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Autors principals:	Line M. Myklebust, Markus Baumann, Svein I. Støve, Håvard Foyn, Thomas Arnesen, Bengt Erik Haug
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-06-01
Col·lecció:	Frontiers in Chemistry
Matèries:	bisubstrate inhibitor N-terminal acetylation acetyltransferase NAA80 actin cytoskeleton
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fchem.2023.1202501/full
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