Low Depth Epigenetic Mapping of Maturation Versus Retrodifferentiation in HepaRG Cells

<b>Background:</b> Long-read, single-CpG-resolution sequencing is redefining the information-to-depth ratio in epigenomics. While conventional methylome analysis often requires high coverage, we propose a scalable pipeline designed to extract high-density regulatory logic from shallow sequencing dat...

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Bibliografske podrobnosti

Principais autores:	Hector Hernandez-Vargas, Kilian Petitjean, Marie-Pierre Lambert, Yoann Daniel, Isabelle Chemin, Anne Corlu, Chloe Goldsmith
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2026-06-01
Serija:	Epigenomes
Teme:	DNA methylation long read sequencing cell fate decisions
Online dostop:	https://www.mdpi.com/2075-4655/10/2/36
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