Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues

Abstract Aberrantly accumulated metabolites elicit intra- and inter-cellular pro-oncogenic cascades, yet current measurement methods require sample perturbation/disruption and lack spatio-temporal resolution, limiting our ability to fully characterize their function and distribution. Here, we show t...

Полное описание

Библиографические подробности

Главные авторы:	Marlous Kamp, Jakub Surmacki, Marc Segarra Mondejar, Tim Young, Karolina Chrabaszcz, Fadwa Joud, Vincent Zecchini, Alyson Speed, Christian Frezza, Sarah E. Bohndiek
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2024-06-01
Серии:	Nature Communications
Online-ссылка:	https://doi.org/10.1038/s41467-024-49403-w
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