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Characterization of novel arrhythmogenic patterns arising secondary to heterogeneous expression and activation of Nav1.8

BackgroundPrevious studies suggested that SCN10A/Nav1.8 may influence cardiac electrophysiology and the susceptibility to cardiac arrhythmias. Notably, the expression of SCN10A is not uniform, showing variable expression in each cardiac chamber. The present study aims to explore the functional signi...

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Hauptverfasser: Zhong-He Zhang, Hector Barajas-Martinez, Hong-Yi Duan, Guo-Hua Fan, Hong Jiang, Charles Antzelevitch, Hao Xia, Dan Hu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2025-03-01
Schriftenreihe:Frontiers in Cardiovascular Medicine
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1546803/full
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