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Camel Hemorphins Exhibit a More Potent Angiotensin-I Converting Enzyme Inhibitory Activity than Other Mammalian Hemorphins: An In Silico and In Vitro Study

Angiotensin-I converting enzyme (ACE) is a zinc metallopeptidase that has an important role in regulating the renin-angiotensin-aldosterone system (RAAS). It is also an important drug target for the management of cardiovascular diseases. Hemorphins are endogenous peptides that are produced by proteo...

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Principais autores: Amanat Ali, Seham Abdullah Rashed Alzeyoudi, Shamma Abdulla Almutawa, Alya Nasir Alnajjar, Yusra Al Dhaheri, Ranjit Vijayan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-03-01
coleção:Biomolecules
Assuntos:
hemorphins
angiotensin-i converting enzyme
anti-hypertension
molecular docking
molecular dynamics
Acesso em linha:https://www.mdpi.com/2218-273X/10/3/486
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