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Non-clinical assessment of safety, biodistribution and tumorigenicity of human mesenchymal stromal cells

Guidelines regulating the development of advanced therapy medicinal products (ATMPs) request nonclinical data for toxicity, biodistribution and tumorigenicity before mesenchymal stromal cell (MSC) products can be administered in large clinical trials. We assessed the biodistribution/persistence, saf...

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Bibliografiske detaljer
Principais autores: Claudia Thäte, Christiane Woischwill, Gunda Brandenburg, Matthias Müller, Sonja Böhm, Joachim Baumgart
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021-01-01
Serier:Toxicology Reports
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S2214750021002006
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