Taok1 haploinsufficiency leads to autistic-like behaviors in mice via the dorsal raphe nucleus

Summary: Strong evidence from human genetic studies associates the thousand and one amino acid kinase 1 (TAOK1) gene with autism spectrum disorder (ASD). In this work, we discovered a de novo frameshifting mutation in TAOK1 within a Chinese ASD cohort. We found that Taok1 haploinsufficiency induces...

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Autors principals:	Jincheng Wang, Weike Li, Zimeng Li, Zhenyu Xue, Yuefang Zhang, Yiting Yuan, Yuhan Shi, Shifang Shan, Wenjian Han, Fei Li, Zilong Qiu
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2023-09-01
Col·lecció:	Cell Reports
Matèries:	CP: Neuroscience
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2211124723010896
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