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Human FOXP3 Isoforms in Health and Disease

Forkhead box P3 (FOXP3) is the master transcription factor of regulatory T cells (Tregs) and is essential for maintaining immune tolerance. FOXP3 is stably expressed in Tregs, driving their suppressive function, and it is transiently induced in conventional T cells (Tconv) upon activation, where it...

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Detalles Bibliográficos
Principais autores: Merve Nida Gokbak, Akshaya Ramachandran, Eden Micaelian, Megan Cooper, Giorgia Bucciol, Leonardo Oliveira Mendonça, Clinton Dunn, Hey Jin Chong, Jacques G. Rivière, Eyal Kristal, Hiba Mohammed Shendi, Jessie Alexander, Rosa Bacchetta
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2026-05-01
Series:Journal of Human Immunity
Acceso en liña:https://rupress.org/jhi/article/2/CIS2026/eCIS2026abstract.153/282017/Human-FOXP3-Isoforms-in-Health-and-Disease
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