Integrated Quantitative Proteomics and Metabolome Profiling Reveal MSMEG_6171 Overexpression Perturbing Lipid Metabolism of Mycobacterium smegmatis Leading to Increased Vancomycin Resistance

In recent years, the treatment of tuberculosis is once again facing a severe situation because the existing antituberculosis drugs have become weaker and weaker with the emergence of drug-resistant Mycobacterium tuberculosis (Mtb). The studies of cell division and cell cycle-related factors in Mtb a...

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Autori principali:	Zhuhua Wu, Wenjing Wei, Ying Zhou, Huixin Guo, Jiao Zhao, Qinghua Liao, Liang Chen, Xiaoli Zhang, Lin Zhou
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2020-07-01
Serie:	Frontiers in Microbiology
Soggetti:	MSMEG_6171 lipid metabolism Mycobacterium smegmatis drug resistance multi-omics
Accesso online:	https://www.frontiersin.org/article/10.3389/fmicb.2020.01572/full
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