Effect of Bexarotene on Platelet Activation and Apoptosis

Background/Aims: The retinoid X receptor (RXRs) stimulator Bexarotene ((4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl] benzoic acid) is used for the treatment of several malignancies. Bexarotene is at least in part effective by stimulation of apoptosis of tumor cells. Moreover, B...

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Principais autores:	Hang Cao, Rosi Bissinger, Anja T. Umbach, Meinrad Gawaz, Florian Lang
格式:	Artigo
語言:	Inglês
出版:	Cell Physiol Biochem Press GmbH & Co KG 2017-06-01
叢編:	Cellular Physiology and Biochemistry
主題:	Collagen related peptide Platelet activation Degranulation Integrin Cytosolic Ca2+ concentration Caspase Phosphatidylserine Thrombin
在線閱讀:	http://www.karger.com/Article/FullText/478627
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