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Development of HPMC-Based Hard Capsules with Rapid Disintegration Across Simulated Gastrointestinal pH Conditions: Formulation Design, Process Optimization, and Disintegration Mechanism of the HPMC/GG/ι-C Ternary System

While hydroxypropyl methylcellulose (HPMC) is a promising plant-based alternative to gelatin, its industrial application is limited by poor mechanical properties and high production costs. In this study, high-performance HPMC-based hard capsules were developed using an HPMC/gellan gum/ι-carrageenan...

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Principais autores: Yuting Dong, Songlin Ye, Xiaojun Hong, Yafang Shi, Youcheng Liu, Xueqin Zhang, Jing Ye, Meitian Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2026-05-01
coleção:Marine Drugs
Assuntos:
hydroxypropyl methylcellulose
gellan gum
ι-carrageenan
hard capsules
Acesso em linha:https://www.mdpi.com/1660-3397/24/5/162
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