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Pyroptosis, superinfection, and the maintenance of the latent reservoir in HIV-1 infection

Abstract A long-lived reservoir of latently infected T cells prevents antiretroviral therapy from eliminating HIV-1 infection. Furthering our understanding of the dynamics of latency generation and maintenance is therefore vital to improve treatment outcome. Using mathematical models and experiments...

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Autors principals: Dominik Wodarz, David N. Levy
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2017-06-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-017-04130-9
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