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Manual Hippocampal Subfield Segmentation Using High-Field MRI: Impact of Different Subfields in Hippocampal Volume Loss of Temporal Lobe Epilepsy Patients

In patients with temporal lobe epilepsy (TLE), presurgical magnetic resonance imaging (MRI) often reveals hippocampal atrophy, while neuropathological assessment indicates the different types of hippocampal sclerosis (HS). Different HS types are not discriminated in MRI so far. We aimed to define th...

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Main Authors: Jose Eduardo Peixoto-Santos, Luciana Estefani Drumond de Carvalho, Ludmyla Kandratavicius, Paula Rejane Beserra Diniz, Renata Caldo Scandiuzzi, Roland Coras, Ingmar Blümcke, Joao Alberto Assirati, Carlos Gilberto Carlotti, Caio Cesar Marconato Simoes Matias, Carlos Ernesto Garrido Salmon, Antonio Carlos dos Santos, Tonicarlo R. Velasco, Marcio Flavio D. Moraes, Joao Pereira Leite
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neurology
Subjects:
high field MRI
hippocampal subfield volumetry
neuronal density
hippocampal sclerosis
4.7T
ex vivo imaging
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00927/full
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