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TREM2 Alleviates Neuroinflammation by Maintaining Cellular Metabolic Homeostasis and Mitophagy Activity During Early Inflammation

Aims: Inflammation is a pivotal characteristic of neurodegenerative diseases. The triggering receptor expressed on the myeloid cells 2 (TREM2) gene has previously been shown to suppress inflammation by directly inhibiting inflammation-related pathways. Mitochondrial dysfunction has recently emerged...

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Principais autores: Lingfeng Hu, Jie Liu, Jie Peng, Xiao Li, Zhangqiong Huang, Caixing Zhang, Shengtao Fan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2025-02-01
Series:Diseases
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Acceso en liña:https://www.mdpi.com/2079-9721/13/2/60
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