Schistosoma mansoni Sirtuins: characterization and potential as chemotherapeutic targets.
The chemotherapy of schistosomiasis currently depends on the use of a single drug, praziquantel. In order to develop novel chemotherapeutic agents we are investigating enzymes involved in the epigenetic modification of chromatin. Sirtuins are NAD+ dependent lysine deacetylases that are involved in a...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science (PLoS)
2013-01-01
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| Sarja: | PLoS Neglected Tropical Diseases |
| Linkit: | http://europepmc.org/articles/PMC3772001?pdf=render |
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