<i>Akkermansia muciniphila</i> Metabolite Inosine Inhibits Castration Resistance in Prostate Cancer

Prostate cancer (PCa) is initially sensitive to androgen deprivation therapy (ADT) but ultimately develops resistance and progresses to castration-resistant prostate cancer (CRPC) with a poor prognosis. This study indicated that some PCa patients and mice were more sensitive to ADT and entered CRPC...

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Autori principali:	Yao Yu, Leqian Li, Qishen Yang, Jingwen Xue, Benlin Wang, Ming Xie, Wentai Shangguan, Zhangrui Zhu, Peng Wu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-08-01
Serie:	Microorganisms
Soggetti:	castration-resistant prostate cancer gut microbiota androgen deprivation therapy <i>Akkermansia muciniphila</i> inosine
Accesso online:	https://www.mdpi.com/2076-2607/12/8/1653
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