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NELL-1-loaded GelMA-fibrinogen crosslinked hydrogel maintains periosteum stability to promote stem cell enrichment and osteogenesis

Jawbone defects pose significant challenges for oral implantation and restoration. Guided bone regeneration is the most common strategy for bone augmentation. However, inadequate efficiency of osteogenesis remains a persistent issue. Periosteum serves as a potential source of osteogenesis, but insuf...

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Principais autores: Jingxia Chen, Jing Xu, Huixin Lv, Jiaxin Luo, Zhen Ci, Yangfan Pei, Yihan Wang, Xiuyu Liu, Sicong Ren, Sheng Chen, Siyu Chen, Ting Zhu, Jingjie Zhai, Yanmin Zhou
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-01-01
Serier:Materials & Design
Fag:
Hydrogel
Intramembranous osteogenesis
Maxillary sinus membrane
Fibrinogen
Online adgang:http://www.sciencedirect.com/science/article/pii/S0264127525017046
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