Bruceine A protects nuclear receptor 4A1 from ubiquitin-degradation to alleviate mesangial proliferative glomerulonephritis

Abstract The nuclear receptor 4A1(NR4A1) plays a crucial role in maintaining cellular homeostasis and is involved in various disease processes; however, its functional role and pharmacological potential in mesangial proliferative glomerulonephritis (MsPGN) remain unexplored. In this study, we found...

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主要な著者:	Huating Hu, Runze Li, Kancheng He, Lingling Wu, Rongrong Li, Jiayan Lu, Ruimin Tian, Chuanghai Zhang, Jiayan He, Yulian Chen, Ruogu Lai, Jiaqi Zhang, Jiaqi Wu, Ying Zheng, Jinlian He, Liang Liu, Xiangmei Chen, Hudan Pan
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Publishing Group 2025-12-01
シリーズ:	Signal Transduction and Targeted Therapy
オンライン･アクセス:	https://doi.org/10.1038/s41392-025-02495-2
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