Regulation of the PI3K pathway through a p85α monomer–homodimer equilibrium
The canonical action of the p85α regulatory subunit of phosphatidylinositol 3-kinase (PI3K) is to associate with the p110α catalytic subunit to allow stimuli-dependent activation of the PI3K pathway. We elucidate a p110α-independent role of homodimerized p85α in the positive regulation of PTEN stabi...
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
eLife Sciences Publications Ltd
2015-07-01
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| Цуврал: | eLife |
| Нөхцлүүд: | |
| Онлайн хандалт: | https://elifesciences.org/articles/06866 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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